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Symposium
2006 |
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관련사이트 |
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| Advantages of Robotic Surgery
In today's operating rooms, you'll find
two or three surgeons, an anesthesiologist and
several nurses, all needed for even the simplest of surgeries. Most surgeries
require nearly a dozen people in the room. As with all automation, surgical
robots will eventually eliminate the need for some of that personnel. Taking a
glimpse into the future, surgery may require only one surgeon, an
anesthesiologist and one or two nurses. In this nearly empty operating room, the
doctor will sit at a computer console, either in or outside the operating room,
using the surgical robot to accomplish what it once took a crowd of people to
perform.
The use of a computer console to perform operations from a distance opens up
the idea of tele-surgery, which would involve a doctor performing
delicate surgery miles away from the patient. If the doctor doesn't have to
stand over the patient to perform the surgery, and can remotely control the
robotic arms at a computer station a few feet from the patient, the next step
would be performing surgery from locations that are even farther away. If it
were possible to use the computer console to move the robotic arms in
real-time, then it would be possible for a doctor in California to
operate on a patient in New York. A major obstacle in tele-surgery has been the
time delay between the doctor moving his or her hands to the robotic arms
responding to those movements. Currently, the doctor must be in the room with
the patient for robotic systems to react instantly to the doctor's hand
movements.
Having fewer personnel in the operating room and allowing doctors the ability
to operate on a patient long-distance could lower the cost of health care. In
addition to cost efficiency, robotic surgery has several other advantages over
conventional surgery, including enhanced precision and reduced trauma to the
patient. For instance, heart bypass surgery
now requires that the patient's chest be "cracked" open by way of a 1-foot
(30.48-cm) long incision. However, with the da Vinci or ZEUS systems, it is
possible to operate on the heart by making three
small incisions in the chest, each only about 1 centimeter in diameter. Because
the surgeon would make these smaller incisions instead of one long one down the
length of the chest, the patient would experience less pain and less bleeding,
which means a faster recovery.
Robotics also decrease the fatigue that doctors experience during surgeries
that can last several hours. Surgeons can become exhausted during those long
surgeries, and can experience hand tremors as a result. Even the steadiest of
human hands cannot match those of a surgical robot. The da Vinci system has been
programmed to compensate for tremors, so if the doctor's hand shakes the
computer ignores it and keeps the mechanical arm steady.
While surgical robots offer some advantages over the human hand, we are still
a long way from the day when autonomous robots will operate on people without
human interaction. But, with advances in computer power and artificial
intelligence, it could be that in this century a robot will be designed that can
locate abnormalities in the human body, analyze them and operate to correct
those abnormalities without any human guidance.
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| How Artificial Hearts Work
Your heart is the
engine inside your body that keeps everything running. Basically, the heart is a
muscular pump that maintains oxygen and blood circulation through
your lungs and body. In
a day, your heart pumps about 2,000 gallons of blood. Like any engine, if the
heart is not well taken care of it can break down and pump less efficiently, a
condition called heart failure.
Until recently, the only option for many severe heart failure patients has
been heart transplants. However, there are only slightly more than 2,000 heart
transplants performed in the United States annually, meaning that tens of
thousands of people die waiting for a donor heart. On July 2, 2001, heart
failure patients were given new hope as surgeons at Jewish
Hospital in Louisville, Kentucky, performed the first artificial heart
transplant in nearly two decades. The AbioCor Implantable Replacement
Heart is the first completely self-contained artificial heart and is
expected to at least double the life expectancy of heart patients.
In this article, you will get an in-depth look at how this new artificial
heart works, how it's implanted into a patient's chest and who might be a
candidate for receiving one of these mechanical hearts. We will also compare the
AbioCor heart to the artificial hearts that have failed in the past.
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Signal Transduction — Targeting Cancer at the Molecular
Level
New understanding of how cancer cells survive, thrive, and metastasize has
enabled researchers to create new targeted therapies for cancer treatments, such
as melanoma and Kaposi's sarcoma, to minimize the harmful systemic effects of
therapy on healthy cells. The specific and selective targets of future oncology
drugs will require a detailed understanding of cancer cell biology, genetics,
immunology, and biotechnology.
The search for anti-cancer therapies which target cancer cells specifically
and selectively with less toxicity has been a quest in oncology for many years.
Conventional chemotherapeutic agents do not target cancer cells selectively,
leading to widespread adverse systemic effects. Chemotherapy, radiation therapy,
and biological agents all target cells that are in the process of proliferation.
Therefore, both cancer cells and mitotically active healthy cells are subject to
the cytotoxic effects of these therapies.
New understanding of how cancer cells survive, thrive, and metastasize has
enabled researchers to create new targeted therapies for cancer
treatments to minimize the harmful systemic effects of therapy on healthy cells.
Cancer therapies are now in development which block or interrupt specific
pathways or proteins that are intricately involved in the proliferation of
cancer cells. Molecular targeting of cancer cells is the prevailing
research field in oncologic pharmacology. The discovery of distinctive molecular
pathways of cancer has engendered new targets for oncology pharmacotherapy. The
specific and selective targets of future oncology drugs will require a detailed
understanding of cancer cell biology, genetics, immunology, and
biotechnology.
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| Innovations in
Treatment of Brain Tumors
There are treatments for all patients with an adult brain
tumor. Three kinds of treatment are used:
surgery,
radiation therapy and chemotherapy
Surgery is
the most common treatment of adult brain tumors. To take out the cancer from the
brain, a doctor will cut a part of the bone from the skull to get to the brain.
This operation is called a craniotomy. After the doctor removes the cancer, the
bone will be put back or a piece of metal or fabric will be used to cover the
opening in the skull.
Radiation therapy uses x-rays produced by a machine called a
linear accelerator or a cobalt machine to kill cancer cells from the outside and
shrink tumors (external-beam radiation therapy). Radiation therapy may also be
used by putting materials that produce radiation (radioisotopes) through thin
plastic tubes into the tumor to kill cancer cells from the inside (internal
radiation therapy).
Chemotherapy uses drugs to kill cancer cells. Chemotherapy
may be taken by pill, or it may be put into the body by a needle in the vein or
muscle. Chemotherapy is called a systemic treatment because the drug enters the
bloodstream, travels through the body, and can kill cancer cells throughout the
body.
Biological therapy (using the body's immune system to fight
cancer) is also being studied in clinical trials. Biological therapy tries to
get the body to fight cancer. It uses materials made by the body or made in a
laboratory to boost, direct, or restore the body's natural defenses against
disease. Biological therapy is sometimes called biological response modifier
therapy or immunotherapy.
Treatment of adult brain tumor depends on the type and stage
of the disease, and the patient's age and overall health.
Standard treatment may be considered because of its
effectiveness in past studies, or participation in a clinical trial may be
considered. Not all patients are cured with standard therapy, and some standard
treatments may have more side effects than are desired. For these reasons,
clinical trials are designed to find better ways to treat cancer patients and
are based on the most up-to-date information. Clinical trials are ongoing in
most parts of the country for most types of adult brain tumor.
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